Endocrine Abstracts

Background: Prolactin hyper secretion is the most common endocrine abnormality due to hypothalamic–pituitary disorders. PRL is the hormone most commonly secreted in excess by pituitary adenomas.Materials and methods: A retrospective study was performed during the period 1998–2007. The diagnose are based on objective examination, hormonal dosage, MRI.Results: During these time were diagnosed 98 cases with hyperprolactinemi...

Introduction: Aim: the aim of our study was to give some data about the epidemiology of thyroid cancer in our country.Material and methods: We studied patients diagnosed with thyroid cancer during January 1998–October 2007.Results: We studied 179 patient from 13 to 80 years diagnosed with thyroid cancer during January 1998–October 2007. Median age at dignoses was: 46.2±14.7 years. According to the gender: females wer...

Introduction: Insulinoma is a rare tumor, with peak incidence at 30 -60 years of age and more frequent in women. It is associated with a myriad of clinical manifestations: from clearly defined adrenergic and neuroglycopenic symptoms to asymptomatic hypoglycemia. We present the case of a 20-year-old patient with pancreatic insulinoma, which was surgically resected only after her second hospitalization due to repeated negative imaging.Case presentation: A ...

Introduction: Graves’ disease is an autoimmune disease that leads to a generalized over activity of the entire thyroid gland (hyperthyroidism). It is caused by TRAb thyrotropin receptor antibodies (TRAb), which bind to receptors on the surface of thyroid cells and stimulate those cells to overproduce and release thyroid hormones. Subacute thyroiditis is presumed to be caused by a viral infection or a postviral inflammatory process. It is a self-l...

Background: Diabetes mellitus (DM) is a common metabolic disorder and is associated with development of chronic macrovascular complications leading to significant morbidity and mortality. The aim of the study was to evaluate the prevalence and clinical profile of macrovascular complications in diabetic patients in Korca, Albania.Material and methods: A total of 456 cases with type 2 DM attending Department of Endocrine (outpatient/inpatient), from Januar...

Acromegaly is a rare disorder with a high morbidity and mortality rate. The diagnosis is typically prolonged over time due to a slow and hidden development of the disease. Current medical therapy for the treatment of acromegaly involves the administration of somatostatin analogues that effectively suppress excess hormone secretion. The objective of this study was to investigate the efficacy of octreotide therapy in acromegalic. A total of 32 patients have been treated with Oct...

Background: Fahr’s Syndrome, also known as striopallidodentate calcinosis is a rare form of neurological disorder characterized by abnormal calcified deposits in basal ganglia, cerebellar and cerebral cortex. Its prevalence goes from 2 to 12.5%. Etiology of this disorder is very wide and involves endocrinopathy, mitochondrial myopathies dermatological abnormalities, infectious disease or may be idiopathic. We present a case of a patient with diffuse brain calcifications d...

Background: Nephrocalcinosis is characterized by the deposition of calcium products in kidney parenchyma and tubules. It may cause acute or chronic kidney injury or be incidentally detected radiographically in a patient with normal kidney function. Most patients with nephrocalcinosis do not progress to end-stage kidney disease, but with certain underlying conditions, may be associated with progressive kidney dysfunction.Methods: The patient was diagnosed...

Introduction: Occult papillary carcinomas are small thyroid carcinomas (<1 cm) diagnosed after an initial manifestation of lymph nodes or distant metastasis. We report two cases of patients with this pattern of clinical presentation.Case description: The first case is a 21-year-old woman, with a one-year history of a growing cervical cyst. Fine needle aspiration of the cyst showed metastasis from papillary thyroid cancer. She had no previous history ...

Introduction: Hypothyroidism is considered refractory to oral levothyroxine substitution, when there is biochemical (serum level of TSH (thyroid stimulating hormone) above the upper target level) or clinical evidence of hypothyroidism, despite increasing dosages of oral levothyroxine beyond 2.5 μg/kg daily. In these circumstances, further increments in the dosage of levothyroxine may not always be the most appropriate intervention. In such a situation, physicians need to ...